FiO2 Totally Explained

Everything about Fio2 totally explained

FiO₂, in the field of medicine, is the fraction of inspired oxygen in a gas mixture. The FiO₂ is expressed as a number from 0 (0%) to 1 (100%). The FiO₂ of normal room air is 0.21 (21%).
A patient's FiO₂ may be varied through the use of different Venturi masks, in combination with varying oxygen flow rates. In addition, most mechanical ventilators have controls for adjusting FiO₂. An increased FiO₂ is necessary in managing adequate oxygenation in patients who are critically ill due to causes such as major surgery, acute lung injury, sepsis, pneumonia, congestive heart failure, or other cardiopulmonary disease. The oxygenation to a patient on a ventilator can be manipulated by changing not only Fio2, but also the tidal volume,the respiratory rate and having a Positive end-expiratory pressure (PEEP). Generally the FiO2 is maintained at less than 40%. Higher settings can lead to oxygen toxicity.
Another common misconception is that the FiO₂ changes with elevation. It remains at 0.21 at all altitudes within the atmosphere. What changes is the barometric pressure of air. At altitude, therefore, the partial pressure of oxygen delivered by that 21% of oxygen is lower. The partial pressure is the driving force to oxygenate the blood and therefore a lower partial pressure makes it that much harder to get O₂ delivered to the tissues that require it, resulting in hypoxia.

Further Information

Get more info on 'Fio2'.

External Link Exchanges

Do you know how hard it is to get a link from a large encyclopaedia? Well we're different and will prove it. To get a link from us just add the following HTML to your site on a relevant page:

<a href="http://fio2.totallyexplained.com">FiO2 Totally Explained</a>

Then simply click through this link from your web page. Our crawlers will verify your link, extract the title of your web page and instantly add a link back to it. If you like you can remove the words Totally Explained and embed the link in article text.
As long as your link remains in place, we'll keep our link to you right here. Please play fair - our crawlers are watching. Your site must be closely related to this one's topic. Any kind of spamming, dubious practises or removing the link will result in your link from us being dropped and, potentially, your whole site being banned.